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UA Life Science Research - BioGate
Raymond B Nagle MD, PhD
Professor and Associate Head
Contact Information
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Address: Arizona Cancer Center
PO 245024
Tucson, AZ 84724-5-24
Phone: 520-626-6032
E-Mail: rnagle@email.arizona.edu
Degrees
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Ph.D., University of Washington
M.D., University of Washington
Department Affiliations
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Pathology, Cell Biology & Anatomy, BIO5 Institute, Arizona Cancer Center
Program Affiliations
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Cancer Biology GIDP
Research Interests
The work in my laboratory primarily focuses on the interaction of cell surface molecules with the extracellular matrix, and migration of cells. These problems are basic to our understanding of the invasion and spread of cancer. We have focused on prostate cancer and use a variety of approaches including protein chemistry, immunohistochemical analysis, ultrastructural analysis, and molecular procedures. Our work includes model systems using prostate cell lines, immunodeficient mice, and human tissues. Opportunities to learn technical procedures include monoclonal antibody production, transfection (using cDNA), and analysis of messenger RNA at the cellular level using in-situ hybridization.
Selected Publications
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