Drug Discovery and Delivery

Migraine drug shows promise in treatment of acute kidney injury

Kidney and Brain displays
MedicalXpress

The drug lasmiditan, which is used to treat migraines, shows promise as a possible treatment for acute kidney injury, according to a new study from the University of Arizona. The findings are published ahead of print in the American Journal of Physiology–Renal Physiology.

Following Nature's Rules

Dr. Robin Polt in a lab holding a canister and smiling.
Arizona Alumni
Neurological disorders are the leading cause of disability and the second-leading cause of death worldwide, but UArizona researchers have developed a new class of drugs that is able to cross the blood-brain barrier and could be used to treat these degenerative neurological diseases and conditions.

Newly Discovered Protein Could Be Used To Produce Life-Saving Antifungals

Yeast with a red fluorescent protein marking the vacuole - the nutrient storage compartment of the cell - and a green fluorescent protein marking aggregates of TORC1 that form in cells missing Ait1.
UArizona News
UArizona researchers have discovered a protein that is responsible for controlling cell growth in yeasts. Since humans and yeasts have remarkably similar cellular mechanisms, teasing out the differences presents drug developers with new targets for treatments.