Craig, Z. R., Davis, J. R., Marion, S. L., Barton, J. K., & Hoyer, P. B. (2010). 7,12-Dimethylbenz[A]Anthracene Induces Sertoli-Leydig-Cell Tumors in the Follicle-Depleted Ovaries of Mice Treated with 4-Vinylcyclohexene Diepoxide. COMPARATIVE MEDICINE, 60(1), 10-17.
BIO5 Collaborators
Jennifer Kehlet Barton, Zelieann R Craig
Luo, Y., Gelsinger, P. J., Barton, J. K., Barbastathis, G., & Kostuk, R. K. (2008). Multiplexing volume holographic gratings for a spectral-spatial imaging system. PRACTICAL HOLOGRAPHY XXII: MATERIALS AND APPLICATIONS, 6912.
Barton, J., Davidson, B. R., & Barton, J. K. (0). Application of optical coherence tomography to automated contact lens metrology. Journal of biomedical optics, 15(1).
Optical coherence tomography (OCT) is a nondestructive imaging modality with the potential to make quantitative spatial measurements. OCT's noncontact nature, sensitivity to small refractive index mismatches, and micron-scale resolution make it attractive for contact lens metrology, specifically, measuring prism. Prism is defined as the maximum difference in thickness of the contact lens, measured over a full 360 deg of rotation, at a fixed distance from the contact lens edge. We develop and test a novel algorithm that automatically analyzes OCT images and calculates prism. Images are obtained using a Thorlabs OCT930SR OCT system. The OCT probe is fastened to an automated rotation stage that rotates 360 deg in small increments (typically 10 deg) to acquire OCT images of the edge of the contact lens around the entire circumference. The images are 1.6 mm in optical depth (512 pixels) and 2 mm wide (1000 pixels). Several sets of images are successfully analyzed. The prism measured for a toric lens is 42 microm, which is in line with design parameters. Thickness measurements are repeatable with a standard deviation of 0.5 microm and maximum range of 1.8 microm over ten image sets. This work demonstrates the possibility of using OCT to perform nondestructive contact lens metrology.
Korde, V., Zhao, D., Raghunand, N., Black, J. F., Gillies, R., & Barton, J. K. (2007). Using methemoglobin as a magnetic resonance imaging contrast agent. LASERS IN SURGERY AND MEDICINE, 3-3.
Winkler, A. M., Rice, P., Weichsel, J., Backer, M. V., Backer, J. M., & Barton, J. K. (2009). In vivo imaging using a VEGF-based near-infrared fluorescent probe for early cancer diagnosis in the AOM-treated mouse model. REPORTERS, MARKERS, DYES, NANOPARTICLES, AND MOLECULAR PROBES FOR BIOMEDICAL APPLICATIONS, 7190.